Alpha lipoic acid, mercury redistribution, and safety concerns. It helps mitochondria make more energy. The metal chelator meso-2,3-dimercaptosuccinic acid (DMSA) is considerably less toxic than the classical agent . In another study, lipoic acid can significantly help improve some types of scars. Your blood levels of your chelator will have dropped too much with the late dose inducing a lot of redistribution of mercury. every 3 hours. At the same time, ALA is a supplement used by probably millions of people for neuropathy and as an antioxidant. These qualities allow alpha lipoic acid benefits to extend to a wide range of health issues and conditions. Because it acts like an antidote to oxidative stress and inflammation, alpha lipoic acid seems to fight damage done to the blood vessels, brain, neurons and organs, like the heart or liver. Alpha-lipoic acid is a powerful supplement you can use to help prevent oxidative stress. National Institutes of Health. A significant portion of the country has amalgam fillings. Subject: ALA and redistribution of mercury; Date: Sat, 28 Jun 2003 16:00:19 -0000; Yahoo! This bottle of high-strength ALA contains 120 capsules of 99% alpha-lipoic acid, each containing 500 mg, for $18.97. Alpha-Lipoic Acid Alpha-Lipoic Acid Alpha-Lipoic Acid 90 veggie capsules - $15.95 Alpha-lipoic acid is equally important for it will, along with selenium, raise glutathione levels. Andy Cutler warns against supplementing with ALA irregularly for the risk of mercury redistribution in the brain and organs. Reply. Alpha-Lipoic acid also balances blood glucose levels and increases insulin sensitivity, which can help manage diabetes while also assisting the body in promoting weight loss. The theorists reasoned that if mercury was the cause of autism, then removing mercury from the body would cure autism. (Lipoic acid can sometimes impede the body's removal of copper. I take HM CHELATE by 'Pure Encaspulation'- it's FOR the purpose of removing metals and it contains alpha lipoic acid, chlorella, cilantro, l-methionine, NAC, zinc, selenium, and some other citrus derivatives. . Andy Cutler warns against supplementing with ALA irregularly for the risk of mercury redistribution in the brain and organs. Mercury is highly neurophilic (strong affinity for nervous tissue) and highly lipophilic (binds tightly to fatty tissue). RESULTS:None of these regimens reduced the mercury content of the brain. Antioxidants attack "free radicals," waste products created when the body turns food into energy. ALA is a potent antioxidant and regenerates other antioxidants. term lasting problems are due to mercury redistribution. Alpha-lipoic acid, a coenzyme of pyruvate and alpha-ketoglutarate dehydrogenase, has been used in Germany as an antioxidant and approved treatment for diabetic polyneuropathy for 40 years. Has Anti-Inflammatory and Antioxidant Effects. 24. . This ALA is encapsulated in vegetarian capsules and is highly bioavailable. Answer (1 of 2): It is very harmful. DMSA, DMPS and ALA (Alpha-Lipoic Acid) are good for Mercury, but see below about ALA and brain blood barrier. It's called "redistribution". The experiments showed that alpha lipoic acid dramatically increased the excretion of Hg++ into bile. Subject: Re: Alpha Lipoic Acid as an antioxidant; Date: Fri, 16 Jul 2004 07:20:24 -0000; Yahoo! Side effects only start to be felt at higher doses. The present article reviews the clinical use of thiol-based metal chelators in intoxications and overexposure with mercury (Hg), cadmium (Cd), and lead (Pb). It enables the mercury to flood into your brain. Now we're getting to more powerful detox supplements. Alpha-Lipoic Acid is a powerful antioxidant and is know to expel mercury from the brain. Shade theorizes that the observed increase of Hg++ in bile is the result of alpha lipoic acid . 2) Alpha-Lipoic Acid. Alpha-Lipoic Acid is a powerful antioxidant and is know to expel mercury from the brain. On a per calorie basis, broccoli actually contains more protein than steak. term lasting problems are due to mercury redistribution. It is very important that Alpha Lipoic Acid or any chelator is taken on its half-life rather than randomly. Subject: Re: Alpha Lipoic Acid as an antioxidant; Date: Fri, 16 Jul 2004 07:20:24 -0000; Yahoo! These side effects can include upset stomach, nausea, diarrhea, flatulence and the likes. If there are any side-effects monitor these and if too intense, stop, wait a few days and start on a lower dose, such as 10mg or 6mg. Alpha Lipoic Acid (ALA, thioctic acid, pyruvate oxidation factor) was first discovered by bacteriologist Irwin C. Gunsalus in 1948 when he observed that aerobic (oxygen-requiring) bacteria could not grow without it. Alpha-Lipoic Acid (ALA) is a sulfur-containing fatty acid naturally found in your body. It is an organosulfur compound and is produced in the body of humans and animals. If you have a source of that heavy metal in the body - as you do with "silver" fillings - one should be able to deduce that the . ALA Benefits. Alpha-Lipoic-Acid-300 (alpha-lipoic acid) for Dietary Supplementation: "I took a total of 400-600 mgs daily for burning mouth syndrome. The results would be redistribution and chronic sickness. It has the ability to scavenge free radicals in a very efficient manner and also enhances the production of glutathione. ALA is made in animals normally, and is essential for aerobic metabolism.It is also manufactured and is available as a dietary supplement in some countries where it is marketed as an antioxidant, and is available as a pharmaceutical . ( Wikipedia) Alpha Lipoic Acid is involved in aerobic metabolism, such as breathing. Lipoic acid | C8H14O2S2 | CID 6112 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. I don't remember exactly why, but I most certainly . 1999 Jan;39(1):67-80. Improves several components of the metabolic syndromea combination of risk factors that increases one's risk for diabetes 6. Maybe cut the dose in half and see if you get the same benefits without the downside. It is also a potent antioxidant that has been used to treat a variety of conditions, including diabetes, AIDS, cancer, hypertension . Alpha lipoic acid is a compound found naturally inside every cell in the body. National Library of Medicine. David Tomen says. Thus, it is hard for patients and doctors to see the cause and effect. -- in other words "other" kinds of problems. Alpha lipoic acid is one of the key mitochondrial antioxidants, mitochondria are found in all cells of the body and known as the 'energy centres' of the cell. These absolutely should not be taken unless all amalgam fillings have been removed. Alpha-lipoic acid is an antioxidant derived from caprylic acid. Alpha-lipoic acid is an antioxidant also known as Acetate Replacing Factor, ALA, Biletan, Lipoicin, Thioctan, and many other names. Supposedly, if you don't, you risk just moving the mercury around from one place in the body to another, just doing more damage. Scientists are researching whether it can bind to heavy metals in the brain and reduce damage to cellular membranes [34, 35, 36]. It's the Universal Antioxidant. Lipoic acid pulls mercury out of your tissue. . Needless to say, I was very constipated. Alpha-lipoic acid is an antioxidant made by the body. If you aren' t mercury or copper poisoned, then 300 mg per day appears safe. Research has attempted to identify the role of antioxidants, glutathione and alpha-lipoic acid specifically, in both mitigation of heavy metal toxicity and . 2001;276(42):38329-38336. It temporarily alleviated some moderate insomnia. Alpha lipoic acid is another supplement with multiple benefits. Because of its two sulfurs, ALA can bind and transport mercury for excretion from the body. These absolutely should not be taken unless all amalgam fillings have been removed. Years ago (before I knew about mercury poisoning, let alone that I had been poisoned by the "harmless" amalgams) I took one tablet of supposedly wonderful ala. One serving of it (the NLEA serving size of 148 grams) provides 4.2 grams of protein and only 50 calories. Broccoli has more protein than steak. Related Papers. Along with selenium, ALA will help us deal with mercury that is polluting the body. Has Anti-Inflammatory and Antioxidant Effects. Alpha-lipoic acid is a naturally occurring fatty acid that can . If it is not safe because of this, should anyone be taking it at all? This graphic demonstrates the outcomes of both proper and improper use use of alpha lipoic acid. Reduces oxidative stress in the body via powerful antioxidant activity 1,3-5. Alpha lipoic acid (also known as dihydrolipoic acid, lipoic acid, lipolate or thiotic acid) Cysteine (also called acetylcysteine, cystein, cystin, L-cysteine, N-acetylcysteine, or NAC) It's needed by the body to produce the energy for our body's normal functions. Magis D, Ambrosini A, Sandor P, Jacquy J, Laloux P, Schoenen J. Alpha Lipoic Acid have benefit for skin cells and improve skin texture and wrinkles. Alpha-lipoic acid, a coenzyme of pyruvate and alpha-ketoglutarate dehydrogenase, has been used in Germany as an . But Andy talks about "bouncing mercury around" and is that redistribution or not? David Tomen says. In addition, research suggests. Originally ALA was thought to be a vitamin, but then it was discovered that the human body produces it on its own. Stop taking alpha-lipoic acid and call your doctor at once if you have: low blood sugar-- headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or. Alpha Lipoic Acid and Liver Disease. People who have chronic fatigue syndrome are not advised to use alpha lipoic acid supplements as a substitute or as only medication for medical care. Some people with mercury fillings claim that they had a major mercury and arsenic redistribution that effected their health when they took ALA. Dr. Burt Berkson, PhD, M.D. Vigil M, Berkson BM, Garcia AP, Adverse Effects of High Doses of Intravenous Alpha Lipoic Acid on Liver Mitochondria. ALA's ability to fight oxidative stress is many times more potent . People should therefore take care when using certain detoxification substances and always follow. Alpha-lipoic acid: Alpha-lipoic acid is a strong antioxidant that can renew other antioxidants in the body and chelate metals from the body. One cup (38 calories worth) provides 3 grams of protein. (ii) Alpha lipoic acid is a powerful antioxidant that regenerates other antioxidants (e.g., vitamins E and C, and reduced glutathione) and has metal-chelating activity. From WebMD: Alpha-lipoic acid (ALA) . Because it acts like an antidote to oxidative stress and inflammation, alpha lipoic acid seems to fight damage done to the blood vessels, brain, neurons, and organs like the heart or liver. LA contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. Again, that is a monster dose for some people. I'm reducing my dose drastically because the BMS pain is so bad and I'm searching for relief. Toniq is a major name when it comes to both purity and potency. Diabetes. So make sure you are not copper poisoned before trying the lipoic acid.) This article is being expanded over time. No clinical trial has examined the use of lipoic acid as a chelating agent in mercury toxicity, yet it has proven to be effective in several mammalian species . [i] ALA (alpha lipoic acid) is an enzyme found throughout the body and a key component of mitochondria, which produce energy for cells. Alpha Lipoic Acid (ALA) is also known as Lipoic Acid or Thiotic Acid. 3. Alpha-lipoic acid can be eaten in foods,. 649. -- in other words "other" kinds of problems. National Center for Biotechnology Information. March 21, 2021 at 4:33 pm. . ALA is supposed to mobilize mercury from the places it gets sequestered, which is why you need to maintain a constant dose of ALA while you're taking it, and until the mercury is eliminated. Later, Gunsalus and Lester Reed determined the true structure and named it ALA (1951). Research has attempted to identify the role of antioxidants, glutathione and alpha-lipoic acid specifically, in both mitigation of heavy metal toxicity and . Now we're getting to more powerful detox supplements. Anti-oxidant: Alpha lipoic acid serves to recycle other anti-oxidants like Vitamin E and Vitamin C. Whereas the latter work in either It is involved in a variety of reactions, such as the conversion of pyruvate and other alpha-keto acids in the Krebs cycle. Glutathione is one of the main antioxidants your body naturally produces. Alpha-Lipoic Acid (ALA) is a sulfur-containing fatty acid naturally found in your body. Alpha-lipoic acid, a coenzyme of pyruvate and alpha-ketoglutarate dehydrogenase, has been used in Germany as an antioxidant and approved treatment for diabetic polyneuropathy for 40 years. Keeping a steady state level of alpha lipoic acid in the bloodstream will minimize redistribution of mercury into the central nervous system, but it is quite inconvenient and difficult to perform. These radicals can destroy healthy cells and affect cell aging, rendering alpha-lipoic acid . This article is being expanded over time. Alpha lipoic acid is also known as the universal antioxidant. J Biol Chem. The health benefits of alpha lipoic acid include supporting conditions such as: Multiple sclerosis. Alpha-lipoic acid, a coenzyme of pyruvate and alpha-ketoglutarate dehydrogenase, has been used in Germany as an antioxidant and approved treatment for diabetic polyneuropathy for 40 years. Alpha-lipoic acid is an antioxidant that is made naturally in the body and also found in foods. The antioxidant property of ALA explains its protective action in diabetic and chemotherapy-induced neuropathy. Alpha Lipoic Acid (ALA) is a mercury-chelating antioxidant. Free radicals cause harmful chemical reactions that can damage cells, making it harder for the body to fight off infections. It when ALA grabs Mercury from one location and drops is after its half life. 1. Chelating with the Andrew Cutler Protocol involves the following three chelators: ALA (Alpha Lipoic Acid), half life: 3 hours Pharmacol Res. Reed LJ. It is an organic sulfur compound made up of left and right components. Lipoic acid (LA), also known as -lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). A harmful chelation protocol is one that causes preferential redistribution of mercury from less sensitive to more sensitive locations in the body. To put it simply, mercury in the brain, liver, thyroid, adrenal glands and immune system cells will cause more serious damage because these organs and systems are sensitive. Alpha-lipoic acid 600mg helps in the regeneration of antioxidants such as Vitamins E and C and glutathione in the body. Anuradha B, Varalakshmi P. Protective role of DL-alpha-lipoic acid against mercury-induced neural lipid peroxidation. antioxidant protection in the prevention of neurological and renal damage caused by mercury toxicity. Sulfur-containing compounds can complex with heavy metals, and the sulfur antioxidants alpha-lipoic acid (ALA) and glutathione have been demonstrated to chelate a number of metals in cell culture (mercury for glutathione; cadmium, lead, zinc, cobalt, nickel, iron, and copper for ALA) (Patrick 2002). Both fat and water soluble, it is readily absorbed from the gut and crosses cellular and blood-brain membrane barriers [ 22, 53 ]. Chelating with amalgam leftovers can result in a mobilization and redistribution of mercury into the Central Nervous System. Improves the lipid profile. It is used to break down carbohydrates and to make energy. Toniiq Alpha Lipoic Acid. . Alpha-Lipoic Acid and Glutathione. Selenium: Selenium may help remove mercury from the body. a light-headed feeling, like you might pass out. Improper use is what leads pushes mercury into the brain and nervous system causing many of the symptoms you will read in the testimonials below. Keeping a steady state level of alpha lipoic acid in the bloodstream will minimize redistribution of mercury into the central nervous system, but it is quite inconvenient and difficult to perform. Brussel sprouts are also high protein. In particular, it can reach the mercury in your brain and nerve tissue. ALA Benefits. Alpha lipoic acid helps to increase ATP production which isn't just beneficial in reducing fatigue but also helps to increase the cellular . Being low in antioxidants in general can speed up in the aging process, resulting in . When taken at recommended doses, there are no harmful side effects to be expected. PubChem . Aug 24, 2013. #1. Reduces insulin resistance. Certain chelators, such as alpha-lipoic acid, can cause the redistribution of metals in the body. Alpha lipoic acid can relieve nerve pain in peripheral neuropathy. . Lipoic acid (LA), also known as -lipoic acid [2], alpha lipoic acid (ALA) and thioctic acid [3] is an organosulfur compound derived from octanoic acid. March 21, 2021 at 4:33 pm. Alpha-lipoic acid (ALA) is another antioxidant that is hypothesized to have the ability to penetrate the cell membrane as well as cross the blood-brain barrier. It begins as an anti-oxidant which can lower lipid peroxides, continues as a metal detoxifier, acts as a mitochondrial enhancer, and serves to recycle glutathione. A trail of research from lipoic acid to alpha-keto acid dehydrogenase complexes. After a month the pain was still present and my stomach was bloated. Removing the Toxic Sources First A randomized double-blind placebo-controlled trial of thioctic acid in migraine . Antioxidants are important because they can help minimize cell damage that is caused by excessive production of harmful free radicals. Common side effects may include: nausea; or. This mean it offers numerous benefits throughout the whole body, from naturally treating Alzheimer's disease to controlling liver disease. Here are 8 little known benefits of alpha lipoic acid (ALA): 1. Studies also found that alpha-lipoic acid supplements can help with neuropathy -- nerve damage -- caused by diabetes or cancer treatment. In one study, Alpha Lipoic Acid has a high potential to reduce wrinkles and fine lines in the skin by up to 50 percent.
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alpha lipoic acid mercury redistribution
alpha lipoic acid mercury redistribution
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